Nordic ChiCaP (childhood cancer predisposition) network comprises multiple working groups that aim to bring attentiona and expertise to more technical questions within a given research area.
Please, direct inquiries about ongoing research to designated contact persons.
Country abbreviations are included to ease communication.
DISCOVERY GROUP
Discovery of novel gene and rare disease associations with ChiCaP syndromes. Advancing the understanding of hereditary cancers to improve diagnosis and patient outcomes.
Aim to perform clinical, molecular and register-based studies to discover novel:
– ChiCaP associations in already known adult cancer predisposition syndromes
– Congenital malformation/ID syndromes with ChiCaP
– Isolated familial cancer syndromes with ChiCaP
– ChiCaP associations in rare diseases
– Associations to poor outcome and severe toxicity reaction
– Associations to second cancers
> See our active calls for Research Collaboration
PSYCHOSOCIAL GROUP
Harmonizing and advancing research on the psychological and social outcomes of cancer predisposition testing in childhood cancers. We work across quantitative and qualitative research paradigms, including large-scale questionnaire-based, individual interviews, and narrative analysis. Ongoing psychosocial studies utilize surveys and semi-structured interviews with patients, parents, and physicians.
Areas of interest:
– Acceptability of testing
– Multidimensional impact of testing
– Detection and accounting of different needs
– Ethical aspects of testing and counselling
SURVEILLANCE GROUP
Advancing surveillance guidelines for ChiCaP syndromes.
TP53 WORKING GROUP
Disease-causing mutations in TP53 are the most common cause of hereditary cancer; this condition is called Li-Fraumeni syndrome. This working group maintains case numbers, information about penetrance, and de novo findings from each Nordic country.
CMMRD WORKING GROUP
Constitutional mismatch repair deficiency syndrome working group.
EPIDEMIOLOGY GROUP
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PhD FORUM
An informal interdisciplinary forum for doctoral students working on childhood cancer predisposition.
Nordic ChiCaP 